In front of Fabiański, Wan-Bissaka and Vladimír Coufal start as right and left back respectively, on either side of Maximilian Kilman and Todibo in central defence.

In midfield, Mexican international Álvarez is in the starting line-up for the first time this season after recovering from a thigh injury and only starting on the bench against Palace at the weekend.

Álvarez’s partner in the middle is James Ward-Prowse, who also makes his first start of the 2024/25 season after an impressive debut season in Claret and Blue.

Captain Jarrod Bowen could start on the right, as he did against Palace, with Tomáš Souček taking the No. 10 position and Summerville on the left wing.

Füllkrug, who scored 16 goals for Borussia Dortmund last season, including the decisive goal in BVB’s 1-0 semi-final first leg win over Paris Saint-Germain, will be hoping to score his first goal in the Hammers’ colours when he leads the team in east London.

Lopetegui has also named a strong bench, featuring experienced international players Lucas Paquetá, Mohammed Kudus, Michail Antonio, Emerson, Guido Rodríguez and Dinos Mavropanos. Wes Foderingham, Andy Irving and Luis Guilherme complete the matchday squad.

West Ham United: Fabiański, Wan-Bissaka, Todibo, Kilman, Coufal, Álvarez, Ward-Prowse, Souček, Bowen ©, Summerville, Füllkrug
Substitutes: Foderingham (TW), Emerson, Mavropanos, Irving, Paquetá, Rodríguez, Guilherme, Kudus, Antonio

AFC Bournemouth: Neto ©, Smith, Huijsen, Senesi, Hill, Ouattara, Scott, Christie, Tavernier, Sinisterra, Jebbison
Substitutes: Travers (TW), Kerkez, Dennis, Cook, Zabarnyi, Araujo, Kluivert, Semenyo, Evanilson

Referee: Peter Bankes